Publications of Fanis Missirlis (e-links to journals)
grouped by subject
Iron
New molecular components of high and low affinity iron import systems in Drosophila
Soltani S, Yan M, Yu Q, Elhafiz AA, Pfriem E, Webb SM, Kroll T, Bahena-Lopez JM, Missirlis F, King-Jones K. read at publisher - open access
Genes for iron metabolism influence circadian rhythms in Drosophila melanogaster
Mandilaras K, Missirlis F. read at publisher
Iron depletion in the intestines of Malvolio mutant flies does not occur in the absence of a multicopper oxidase
Bettedi L, Aslam MF, Szular J, Mandilaras K, Missirlis F. read at publisher - open access
Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron sulfur cluster enzyme activities and impaired iron homeostasis
Uhrigshardt H, Rouault TA, Missirlis F. read at publisher - open access
Of two cytosolic aconitases expressed in Drosophila, only one functions as an iron regulatory protein
Lind M, Missirlis F, Melefors Ö, Uhrigshardt H, Kirby K, Phillips JP, Söderhäll K, Rouault TA. read at publisher - open access
Mitochondrial iron supply is required for the developmental pulse of ecdysone biosynthesis that initiates metamorphosis in Drosophila melanogaster
Llorens JV, Metzendorf C, Missirlis F, Lind MI. read at publisher
Zinc
Tryptophan regulates Drosophila zinc stores
Garay E, Schuth N, Barbanente A, Tejeda-Guzmán C, Vitone D, Osorio B, Clark AH, Nacthegaal M, Haumann M, Dau H, Vela A, Arnesano F, Quintanar L, Missirlis F. read at publisher - open access
Biogenesis of zinc storage granules in Drosophila melanogaster
Tejeda-Guzmán C, Rosas-Arellano A, Kroll T, Webb SM, Barajas-Aceves M, Osorio B, Missirlis F. read at publisher or bioRxiv preprint
Chloroquine disrupts zinc storage granules in primary Malpighian tubule cells of Drosophila melanogaster
Campos-Blázquez JP, Schuth N, Garay E, Clark AH, Vogelsang U, Nachtegaal M, Contreras RG, Quintanar L, Missirlis F. read at publisher
A recessive X-linked mutation causes a threefold reduction of total body zinc accumulation in Drosophila melanogaster laboratory strains
Afshar N, Argunhan B, Bettedi L, Szular J, Missirlis F. read at publisher - open access
Zinc accumulation in heterozygous mutants of fumble, the pantothenate kinase homologue of Drosophila
Gutiérrez L, Sabaratnam N, Aktar R, Bettedi L, Mandilaras K, Missirlis F. read at publisher - open access
Lower Zinc but Higher Calcium Content in Rodent Spinal Cord Compared to Brain
Santos-Díaz AI, Bizup B, Pantaleón-Gómez AK, Osorio B, Barbier OC, Tzounopoulos T, Missirlis F. read at publisher - open access
Manganese
Intestinal response to dietary manganese depletion in Drosophila
Vásquez-Procopio J, Osorio B, Cortés-Martínez L, Hernández-Hernández F, Medina-Contreras O, Ríos-Castro E, Comjean A, Li F, Hu Y, Mohr S, Perrimon N, Missirlis F. read at publisher
Copper
Diminished spleen iron and kidney copper in the chronic food restricted rat
VSantos-Díaz AI, Osorio B, Guadarrama-Olmos J, Ríos-Castro E, Delgadillo-Álvarez D, Buendía R, Barbier OC, Jiménez-Estrada I, Missirlis F. read at publisher
Molybdenum
The four aldehyde oxidases of Drosophila melanogaster have different gene expression patterns and enzyme substrate specificities
Marelja Z, Dambowsky M, Bolis M, Georgiou ML, Garattini E, Missirlis F, Leimkühler S. read at publisher - open access
Ferritin
Homeostatic mechanisms for iron storage revealed by genetic manipulations of Drosophila ferritin
Missirlis F, Kosmidis S, Brody T, Mavrakis M, Holmberg S, Odenwald WF, Skoulakis EMC, Rouault TA. read at publisher - open access
Ferritin assembly in enterocytes of Drosophila melanogaster
Rosas-Arellano A, Vásquez-Procopio J, Gambis A, Blowes LM, Steller H, Mollereau B, Missirlis F. read at publisher - open access
Ferritin is required in multiple tissues during Drosophila melanogaster development
González-Morales N, Mendoza-Ortíz MA, Blowes LM, Missirlis F, Riesgo-Escovar JR. read at publisher - open access
Biophysical and genetic analysis of iron partitioning and ferritin function in Drosophila melanogaster
Gutiérrez L, Zubow K, Nield J, Gambis A, Mollereau B, Lázaro FJ, Missirlis F. read at publisher
Ferritin accumulation under iron scarcity in Drosophila iron cells
Mehta A, Deshpande A, Bettedi L, Missirlis F. read at publisher
Behavioral decline and premature lethality upon pan-neuronal ferritin over expression in Drosophila infected with a virulent form of Wolbachia
Kosmidis S, Missirlis F, Botella JA, Schnewuly S, Rouault TA, Skoulakis EMC. read at publisher - open access
Ferritin overexpression in Drosophila glia leads to iron deposition in the optic lobes and late onset behavioural defects
Kosmidis S, Botella JA, Mandilaras K, Schneuwly S, Skoulakis EMC, Rouault TA, Missirlis F. read at publisher - open access
Characterization of mitochondrial ferritin in Drosophila
Missirlis F, Holmberg S, Georgieva T, Dunkov BC, Rouault TA, Law JH. read at publisher - open access
Reactive Oxygen Species
Functional characterization of novel thioredoxin reductase and thioredoxin peroxidase in Drosophila
Missirlis F. read here - open access - (Ph.D. Thesis, 2001)
Compartment-specific protection of iron-sulfur proteins by superoxide dismutase
Missirlis F, Hu J, Kirby K, Hilliker A, Rouault TA, Phillips JP. read at publisher - open access
Cooperative action of antioxidant defense systems in Drosophila
Missirlis F, Phillips JP, Jäckle H. read at publisher - open access
Mitochondrial and cytoplasmic thioredoxin reductase variants encoded by a single Drosophila gene are both essential for viability
Missirlis F, Ulschmid JK, Hirosawa-Takamori M, Gronke S, Schafer U, Becker K, Phillips JP, Jäckle H. read at publisher - open access
A putative glutathione peroxidase of Drosophila encodes a thioredoxin peroxidase that provides resistance to oxidative stress but fails to complement for the lack of catalase activity
Missirlis F, Rahlfs S, Dimopoulos N, Bauer H, Becker K, Hilliker A, Phillips JP, Jäckle H. read at publisher
Identification of a selenium-dependent glutathione peroxidase in the blood-sucking insect Rhodnius prolixus
Dias FA, Gandara ACP, Perdomo HD, Goncalves RS, Oliveira CR, Oliveira RLL, Citelli M, Polycarpo CR, Santesmasses D, Mariotti M, Guigó R, Braz GR, Missirlis F, Oliveira PL. read at publisher
Genetic interactions between Drosophila melanogaster Menin and Jun/Fos
Cerrato A, Parisi M, Santa Anna S, Missirlis F, Guru S, Agarwal S, Sturgill D, Talbot T, Spiegel A, Collins F, Chandrasekharappa S, Marx S, Oliver B. read at publisher - open access
Ecological & evolutionary comparisons of insect metallomes
Evidence for evolutionary constraints in Drosophila metal biology
Sadraie M, Missirlis F. read at publisher
Conserved metallomics in two insect families evolving separately for a hundred million years
Rempoulakis P, Afshar N, Osorio B, Barajas-Aceves M, Szular J, Ahmad S, Dammalage T, Tomas US, Nemny-Lavy E, Salomon M, Vreysen MJB, Nestel D, Missirlis F. read at publisher - open access
The genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection
Mesquita RD, Vionette-Amaral RJ, Lowenberger C, Rivera-Pomar R, Monteiro FA, Minx P, Spieth J, Carvalho AB, Panzera F, Lawson D, Torres ALQ, Ribeiro JMC, Sorgine MHF, Waterhouse RM, Montague MJ, Abad-Franch F, Alves-Bezerra M, Amaral LR, Araujo HM, Araujo RN, Aravind L, Atella GC, Azambuja P, Berni M, Bittencourt-Cunha PR, Braz GRC, Calderón-Fernández GM, Carareto CMA, Christensen MB, Costa IR, Costa SG, Dansa M, Daumas-Filho CRO, De-Paula IF, Dias FA, Dimopoulos G, Emrich SJ, Esponda-Behrens N, Fampa P, Fernández-Medina RD, Fonseca RN, Fontenele M, Fronick C, Fulton LA, Gandara ACP, Garcia ES, Genta FA, Giraldo-Calderón GI, Gomes B, Gondim KC, Granzotto A, Guarneri AA, Guigó R, Harry M, Hughes DST, Jablonka W, Jacquin-Joly E, Juárez MP, Koerich LB, Latorre-Estivalis JM, Lavore AE, Lawrence GG, Lazoski C, Lazzari CR, Lopes RR, Lorenzo MG, Lugon MD, Majerowicz D, Marcet PL, Mariotti M, Masuda H, Megy K, Melo ACA, Missirlis F, Mota T, Noriega FG, Nouzova M, Nunes RD, Oliveira RLL, Oliveira-Silveira G, Ons S, Pagola L, Paiva-Silva GO, Pascual A, Pavan MG, Pedrini N, Peixoto AA, Pereira MH, Pike A, Polycarpo C, Prosdocimi F, Ribeiro-Rodrigues R, Robertson HM, Salerno AP, Salmon D, Santesmasses D, Schama R, Seabra-Junior ES, Silva-Cardoso L, Silva-Neto MAC, Souza-Gomes M, Sterkel M, Taracena ML, Tojo M, Tu ZJ, Tubio JMC, Ursic-Bedoya R, Venancio TM, Walter-Nuno AB, Wilson D, Warren WC, Wilson RK, Huebner E, Dotson EM, Oliveira PL. read at publisher
Mosquito metallomics reveal copper and iron as critical factors for Plasmodium infection
Maya-Maldonado K, Cardoso-Jaime V, González-Olvera G, Osorio B, Recio-Tótoro B, Manrique-Saide P, Rodríguez-Sánchez IP, Lanz-Mendoza H, Missirlis F, Hernández-Hernández FC. read at publisher - open access
Cuticle darkening correlates with increased body copper content in Drosophila melanogaster
Vásquez-Procopio K, Rajpurohit S, Missirlis F. read at publisher
Developmental and Nutritional Dynamics of Malpighian Tubule Autofluorescence in the Asian Tiger Mosquito Aedes albopictus
Croce AC, Garbelli A, Moyano A, Soldano S, Tejeda-Guzmán C, Missirlis F, Scolari F. read at publisher - open access
Mitochondria
Female and male gamete mitochondria are distinct and complementary in transcription, structure and genome function
de Paula WBM, Agip ANA, Missirlis F, Ashworth R, Viscay-Barrena G, Lucas CH, Allen JF. read at publisher - open access
Rodent models of human pathophysiology
Metal ion content of internal organs in the calorically restricted Wistar rat
Santos-Díaz AI, Solís-López J, Díaz-Torres E, Guadarrama-Olmos JC, Osorio B, Kroll T, Webb SM, Hiriart M, Jiménez-Estrada I, Missirlis F. read at publisher
Huntington's disease leads to decrease of GABA-A tonic subunits in the D2 neostriatal pathway and their relocalization into the synaptic cleft
Rosas-Arellano A, Tejeda-Guzmán C, Lorca-Ponce E, Palma-Tirado L, Mantellero CA, Rojas P, Missirlis F, Castro MA. read at publisher
Hyperglycemic levels in early stage of diabetic nephropathy affect differentially renal expression of claudins-2 and -5 by oxidative stress
Rosas-Martínez L, Rodríguez-Muñoz R, Namorado-Tonix M, Missirlis F, del Valle-Mondragóna L, Sánchez-Mendoza A, Reyes-Sánchez JL, Cervantes-Pérez LG. read at publisher - open access
Peroxisome Proliferator-Activated Receptor Alpha Stimulation Preserves Renal Tight Junction Components in a Rat Model of Early-Stage Diabetic Nephropathy
Rosas-Martínez L, Rodriguez-Muñoz R, Namorado-Tonix MC, Missirlis F, Valle-Mondragón L, Sánchez-Mendoza A, Reyes-Sánchez JL, Cervantez-Pérez LG. read at publisher - open access
The 24p3 Receptor is implicated in Cadmium-Induced Distal Tubule Nephrotoxicity
Pantaleón-Gómez AK, Avila-Rojas SH, Zavala-Guevara IP, Tostado-Fernández IA, Missirlis F, Aparicio-Trejo OE, Cuevas-López B, León-Contreras JC, Hernández-Pando R, Barbier OC. read at publisher - open access
Hormone replacement therapy for postmenopausal atherosclerosis is offset by late age iron deposition
Xu T, Cai J, Wang L, Xu L, Zhao H, Wang F, Meyron-Holtz E, Missirlis F, Qiao T, Li K. read at publisher - open access
Formation of intraneuronal iron deposits following local release from nanostructured silica injected into rat brain parenchyma
Ortiz-Islas E, Ponce-Juárez AA, Tzompantzi-Morales F, Manríquez-Ramírez ME, Rubio C, Calvillo-Velasco M, Chávez-Cortes G, Missirlis F, Rubio-Osornio M. read at publisher - open access
Iron regulatory protein 2 contributes to antimicrobial immunity by preserving lysosomal function in macrophages
Cheng C, Xing Z, Zhang W, Zheng L, Zhao H, Zhang X, Ding Y, Qiao T, Li Y, Meyron-Holtz EG, Missirlis F, Fan Z, Li K. read at publisher
Clinical studies
Inflammatory-metal profile as a hallmark for COVID-19 severity during pregnancy
Vasquez-Procopio J, Espejel-Nuñez A, Torres J, Sosa EY, Mateu-Rogell P, Ortega-Castillo V, Tolentino-Dolores M, Perichart-Perera O, Franco-Gallardo JO, Carranco-Martínez JA, Prieto-Rodríguez S, Guzmán-Huerta M, Missirlis F, Estrada-Gutierrez G. read at publisher - open access
Association between 25-OH Vitamin D Deficiency and COVID-19 Severity in Pregnant Women
Vásquez-Procopio J, Torres-Torres J, Borboa-Olivares H, Sosa SEY, Martínez-Portilla RJ, Solis-Paredes M, Tolentino-Dolores MC, Helguera-Repetto AC, Marrufo-Gallegos KC, Missirlis F, Perichart-Perera O, Estrada-Gutierrez G. read at publisher - open access
Maternal Metal Ion Status Along Pregnancy and Perinatal Outcomes in a Group of Mexican Women
Vásquez-Procopio J, Torres-Torres J, Rojas-Lima E, Espino Y Sosa S, Solís-Paredes JM, Sánchez-Martínez M, Tolentino-Dolorez MC, Solari PL, Sánchez-López C, Perichart-Perera O, Missirlis F, Estrada-Gutierrez G. read at publisher - open access
Environmental studies
Could the presence of ferrihydrite identified in a riverbed impacted by mining leachates be linked to the reduction in the Contamination and Health Index?
Morales-Mendoza AG, Flores-Trujillo AKI, Del-Razo LM, Peña-Ocaña BA, Missirlis F, Rodríguez-Vázquez R. read at publisher - open access
Techniques
In situ detection of ferric reductase activity in the intestinal lumen of an insect
Hernández-Gallardo AK, Arcos-López T, Bahena-Lopez JM, Tejeda Guzmán C, Gallardo-Hernández S, Webb SM, Kroll T, Solari PL, Sánchez-López C, Den Auwer C, Quintanar L, Missirlis F. read at publisher - open access
Genetic screening for novel Drosophila mutants with discrepancies in iron metabolism
Mehta A, Deshpande A, Missirlis F. read at publisher
A simple solution for antibody signal enhancement in immunofluorescence and immunogold assays
Rosas-Arellano A, Villalobos-González JB, Palma-Tirado L, Beltrán FA, Cárabez-Trejo A, Missirlis F, Castro MA. read at publisher
A low cost antibody signal enhancer improves immunolabeling in cell culture, primate brain and human cancer biopsy
Flores-Maldonado C, Albino-Sánchez ME, Rodríguez-Callejas JD, Estrada-Mondragon A, León-Galicia I, Maqueda-Alfaro R, Perez-Cruz C, Fuchs E, García-Carrancá A, Contreras RG, Missirlis F, Rosas-Arellano A. read at publisher - open access
Review articles, Perspectives, Opinion & Hypothesis
Metal ions in the physiology of insects
Missirlis F, Oliveira PL. read at publisher
Regulation and biological function of metal ions in Drosophila
Missirlis F. read at publisher
Iron sulfur and molybdenum cofactor enzymes regulate the Drosophila life cycle by controlling cell metabolism
Marelja Z, Leimkühler S, Missirlis F. read at publisher - open access
Iron absorption in Drosophila melanogaster
Mandilaras K, Pathmanathan T, Missirlis F. read at publisher - open access
Cellular iron sensing and regulation: Nuclear IRP1 extends a classic paradigm
Gallardo-Hernández K, Missirlis F. read at publisher
Loss of ferritin in developing wing cells: Apoptosis and ferroptosis coincide
Gallardo-Hernández K, Missirlis F. read at publisher - open access
An emerging role for Cullin-3 mediated ubiquitination in sleep and circadian rhythm: Insights from Drosophila
Freeman A, Mandilaras K, Missirlis F, Sanyal S. read at publisher - open access
Drosophila and antioxidant therapy design
Missirlis F, Phillips JP, Jäckle H, Rouault TA. download here
Understanding the aging fly through physiological genetics
Missirlis F. read here
Latrophilins: A Neuro-centric View of an Evolutionary Conserved Adhesion G Protein-Coupled Receptor Subfamily
Moreno-Salinas AL, Avila-Zozaya M, Ugalde-Silva P, Hernández-Guzmán DA, Missirlis F, Boucard AA. read at publisher - open access
Meeting reports
We also CanFly! The 2nd MexFly Drosophila Research Conference
Missirlis F, Nahmad, M. read at publisher
Commentary
Queen Mary: nobody expects the Spanish Inquisition
Allen JF, Missirlis F. read at publisher - open access
